100000 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 100010 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 100020 - Disclosure - Leases - Future Minimum Lease Payments (Detail) 2 link:presentationLink link:calculationLink link:definitionLink 100030 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 100040 - Statement - Condensed Consolidated Statements of Comprehensive Loss 2 link:presentationLink link:calculationLink link:definitionLink 100050 - Statement - Condensed Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 100060 - Statement - Condensed Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 100070 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 100080 - 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Disclosure - Collaborative and Licensing Agreements link:presentationLink link:calculationLink link:definitionLink 100190 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 100200 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 100210 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 100220 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 100230 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 100240 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 100250 - Disclosure - Accrued Expenses (Tables) link:presentationLink link:calculationLink link:definitionLink 100260 - Disclosure - Debt (Tables) link:presentationLink link:calculationLink link:definitionLink 100270 - 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Disclosure - Fair Value Measurements - Schedule of Fair Value, Financial Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation (Details) link:presentationLink link:calculationLink link:definitionLink 100350 - Disclosure - Leases - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100360 - Disclosure - Leases - Schedule of Lease-related Assets and Liabilities (Detail) link:presentationLink link:calculationLink link:definitionLink 100370 - Disclosure - Leases - Schedule of Information Related to Lease Expenses (Detail) link:presentationLink link:calculationLink link:definitionLink 100380 - Disclosure - Leases - Future Minimum Lease Payments (Detail) link:presentationLink link:calculationLink link:definitionLink 100390 - Disclosure - Leases - Schedule of Information Related to the Lease Terms and Discount Rates of Leases (Detail) link:presentationLink link:calculationLink link:definitionLink 100400 - Disclosure - Leases - Schedule of Supplemental Cash Flow Information Related to Leases (Detail) link:presentationLink link:calculationLink link:definitionLink 100410 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Detail) link:presentationLink link:calculationLink link:definitionLink 100420 - Disclosure - Debt - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100430 - Disclosure - Debt - Schedule of Outstanding Borrowings under SVB Term Loan (Detail) 2 link:presentationLink link:calculationLink link:definitionLink 100440 - Disclosure - Debt - Schedule of Outstanding Borrowings under SVB Term Loan (Detail) link:presentationLink link:calculationLink link:definitionLink 100450 - Disclosure - Debt - Schedule of Components of Interest Expense of Term Loan (Detail) link:presentationLink link:calculationLink link:definitionLink 100460 - Disclosure - Stockholders' Equity - Shares Reserved For Future Issuances (Detail) link:presentationLink link:calculationLink link:definitionLink 100470 - Disclosure - Stockholders' Equity - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100480 - Disclosure - Stockholders' Equity - Warrant Activity Including Activity Related To Pre-funded Warrants (Detail) link:presentationLink link:calculationLink link:definitionLink 100490 - Disclosure - Stockholders' Equity (Stock-Based Awards) - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100500 - Disclosure - Stockholders' Equity - Stock Options, Activity (Detail) link:presentationLink link:calculationLink link:definitionLink 100510 - Disclosure - Stockholders' Equity - Stock-based Compensation Expenses (Detail) link:presentationLink link:calculationLink link:definitionLink 100520 - Disclosure - Net Loss per Share - Computation of Basic and Diluted Net Loss Per Share Attributable to Common Stockholders (Detail) link:presentationLink link:calculationLink link:definitionLink 100530 - Disclosure - Net Loss per Share - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100540 - Disclosure - Net Loss per Share - Calculation of Diluted Net Loss Per Share Attributable to Common Stockholders (Detail) link:presentationLink link:calculationLink link:definitionLink 100550 - Disclosure - Collaborative and Licensing Agreements - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100560 - Disclosure - Subsequent Events - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink