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Disclosure - Net Loss per Share - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100630 - Disclosure - Net Loss per Share - Calculation of Diluted Net Loss Per Share Attributable to Common Stockholders (Detail) link:presentationLink link:calculationLink link:definitionLink 100640 - Disclosure - Collaborative and Licensing Agreements - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100650 - Disclosure - Retirement Plan - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100660 - Disclosure - Subsequent Events - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink